Education & Clinical Resources
Understanding the Science of Oral Wound Healing
We're committed to advancing the science of mucosal tissue repair — and to making that science accessible. Explore our growing library of white papers, clinical education resources, and expert webinars designed to support dental professionals and researchers at every stage.
ORIDIVUS
White Papers & Publications
Download peer-reviewed white papers and scientific publications exploring the mechanism, preclinical evidence, and clinical rationale behind ORD002.
ORIDIVUS
Electrospun Nanofiber Technology
Explore the engineering behind ORD002's bioengineered scaffold — how electrospun nanofibers achieve controlled, localized drug delivery over 48–72 hours.
ORIDIVUS
The Science of FTY720 & Immune-Based Healing
Learn how fingolimod (FTY720) modulates the local immune response to accelerate mucosal tissue repair and reduce post-operative pain.
ORIDIVUS | COMING SOON
Expert
Webinars
Live and on-demand webinars led by leading oral surgeons and periodontists. Topics will cover wound healing biology, gingival graft outcomes, and the ORD002 clinical trial.
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ORIDIVUS
Clinical Applications: Gingival Grafts
Understand why gingival graft procedures represent the ideal first indication for ORD002 — including current unmet needs in post-operative healing and pain management.
ORIDIVUS
Patient Education Resources
Downloadable patient-facing materials to help dental practices explain the benefits of ORD002 therapy — including faster healing and reduced opioid use.
Oridivus Science & Clinical Insights
From mechanism of action to clinical evidence, explore the research shaping the future of oral wound care.
PEER REVIEWED PUBLICATION
Regenerative Engineering and Translational Medicine, 2021
Local Delivery of FTY720 Induces Neutrophil Activation Through Chemokine Signaling in an Oronasal Fistula Model
Regenerative Engineering and Translational Medicine, 2021
Early research showing that FTY720 nanofiber scaffolds shift the immune response toward healing in the first days after palatal injury.
→ Read Article: https://pubmed.ncbi.nlm.nih.gov/34722855/
WHITE PAPER
Cleft Palate Repair: A Case for ORD002
Exploring the application of FTY720-eluting nanofiber scaffolds in palatal wound healing and craniofacial reconstruction.
PEER REVIEWED PUBLICATION
Advanced Healthcare Materials, 2024
Accelerating Oral Wound Healing Using Bilayer Biomaterial Delivery of FTY720 Immunotherapy
Advanced Healthcare Materials, 2024
A bilayer FTY720-nanofiber scaffold achieved complete wound closure in an oronasal fistula model by guiding immune and stromal cells toward regeneration.
→ Read Article: https://pubmed.ncbi.nlm.nih.gov/39388502/
CLINICAL REVIEW | COMING SOON
Post-Operative Pain in Gingival Graft Surgery: The Unmet Need
A review of current pain management limitations in soft tissue periodontal procedures and the opportunity for non-opioid alternatives.
PEER REVIEWED PUBLICATION
Biomaterials Advances, 2026
.Investigating FTY720-NF Immunomodulation of Key Lipid, Gene, and Protein Mediators to Enhance Oral Tissue Regeneration
Biomaterials Advances, 2026
Multi-omics analysis of how FTY720 nanofibers reprogram macrophages, with a porcine model showing faster re-epithelialization than platelet-rich plasma controls.
→ Read Article: https://pubmed.ncbi.nlm.nih.gov/42161013/
SCIENCE OVERVIEW | COMING SOON
FTY720 & Mucosal Immunology: How Local Immune Modulation Heals Wounds
An accessible deep-dive into the mechanism of action behind fingolimod and its role in accelerating oral mucosa repair.
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Oridivus
Harnessing immune based healing for breakthrough therapies in oral mucosa wound care.
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